Apetit Block with Sinetrol, a citrus based ingredient specially selected to create a synergy of bioactive polyphenols to enhance weight loss.

Sinetrol® is a patented weight loss ingredient**

The action of Sinetrol® relies on its unique mechanism of action: the Fat Shredding Technology®. The active compounds of Sinetrol® help stimulate lipolysis through the inhibition of phosphodiesterase-4, the enzyme that catalyzes the hydrolysis of cyclic adenosine monophosphate (cAMP). Higher cAMP levels lead to an increased rate of triglyceride breakdown which naturally enhances the release of free fatty acids from the fat cells.


Apetit block is one of the healthiest ways to manage a healthy weight. This innovative formulation contains a blend of polyphenolic compounds and guarana seed extract to help promote healthy weight management.

Apetit Block with Sinetrol®-XPur encourages stored fat to be converted into energy for healthy weight management.

Apetit Block with Sinetrol®-XPur Benefits
Supports healthy weight management
Encourages the breakdown of stored fat
Stop your apetit
Promotes a healthy conversion of fat to energy
This supplement should be taken in conjunction with a healthy diet and regular exercise program. Individual results are not guaranteed, and results may vary.

Maintaining a healthy weight can be a difficult undertaking, but it doesn't have to be. The clinically studied ingredients help encourage the breakdown of stored fat and help support converting that fat into energy.
Made from natural citrus fruit extracts
Orange and grapefruit extracts are selected to create a synergy of bioactive polyphenols targeting body-weight management benefits.Lipolysis is a catabolic process leading to the breakdown of triglycerides stored in fat cells (adipocytes), releasing free fatty acids (FFAs) and glycerol.

Sinetrol Clinical Evidences

Three clinical studies were conducted to investigate the benefits of Sinetrol® on body composition. With results from more than 190 subjects, this natural fat shredder is a proven and safe solution for helping to rid the body of the excess fat mass.

Apetit Block for Weight Management

Apetit block natural formula promotes the metabolism in reducing excess body fat to help reach and maintain a healthy body composition.
Sinetrol® is a patented weight loss ingredient, formulated from natural Mediterranean citrus. Sweet orange, blood orange and grapefruit extracts have been selected to create a synergy of bioactive polyphenols targeting body-weight management benefits. The activity of Sinetrol® is enhanced with natural caffeine from guarana.

How does Apetit Block work?

Stops your apetite!
Containing polyphenol-rich red orange, grapefruit and citrus extracts, Sinetrol® in Apetit Block has shown to reduce body fat by 4.5 percent in one month, in addition to promoting wellness and alertness. Sinterol® works by inhibiting an enzyme that is essential for the formation of triglycerides or fat.
In addition, polyphenols present in Sinetrol® have been reported to help induce the expression of fatty acid oxidation genes, which coax the metabolism toward the use of FFAs to produce additional energy.
Sinetrol® helps stimulate lipolysis* through the inhibition of phosphodiesterase 4 (PDE-4), which leads to the breakdown of triglycerides stored in fat cells (adipocytes) and the release of free fatty acids (FFAs) and glycerol.

To determine the weight-loss benefits of Sinetrol®, a prospective placebo-controlled clinical study was conducted in 20 subjects.

After 3 months, the Sinetrol group lost an average of 5.6kg and 22% of body fat compared to the placebo group.
If you're looking for a natural way to boost your weight loss as part of a healthy lifestyle, try Apetit Block Sinetrol

Further clincal studies on Sinetrol

To further investigate the efficacy and safety of Sinetrol® for body weight management and improvement of metabolic disturbances with reduction in oxidative stress, a second clinical study was performed using Sinetrol® Xpur. This study was published in 2013.​
Sinetrol® helped to enhance body composition*:
Proven fat loss**: supplemented subjects dropped an average 10% of their abdominal fat mass
Waist and hip circumferences were each reduced by an average 5 cm

​​A third clinical study was recently conducted on 77 overweight and obese subjects. Sinetrol® confirms its benefits over 4 months*:
Subjects dropped an average 63% of their excess of body fat mass, as measured by the gold-stand technology DXA (Dual energy X-ray Absorptiometry)
Supplementation led to an increase of resting energy expenditure by 180kcal/day
Not only subjects lost weight but they also significantly gained lean mass, which contributed to a healthier body composition
Dallas C. et al.; Phytomedecine; 2008, 15: 783-792
Dallas C. et al.; Phytother. Res.; 2014, 28(2): 212-218

*These statements have not been evaluated by the Food and Drug Administration.
**This product is not intended to diagnose, treat, cure or prevent any disease.
Before participating in any diet or exercise program, please consult your physician

Sinetrol® helps in supporting the body by:
Proven fat loss: abdominal body fat decreased by 9.73% (p<0.0001) in the Sinetrol® Xpur group (6.55% more than with placebo). Waist and hip circumferences were respectively reduced by 5.15cm and 5.17cm (each, p<0.0001).

Encourages lipolysis: FFA release in the plasma showed significantly higher levels (p<0.0001) in the Sinetrol® Xpur group (more than a 300% increase) compared to the placebo group, in which the increase was only 30%.

Apetit Block Ingredients:

fillers: biologically purified water, vegetable glycerin, acidity corrector: anhydrous citric acid, SINETROL®️ Xpur (hydroethanolic extract from Grapefruit (Citrus paradisi) - 45%, maltodextrin from corn - 30%, Guarana seed extract (Paullinia cupana) - 10%, extract from Sweet Oranges (Citrus sinensis) - 10%, Concentrate from Sweet Oranges (Citrus sinensis) - 5%), containing 20% flavones and 1% - 4% caffeine - 30%, sweetener: xylitol, flavour enhancer: grapefruit (maltodextrin, arabic gum, sugar), preservative: potassium sorbate.

Method of administration: half a teaspoon twice a day, diluted in 200 ml, before main meals (equivalent to 0.9g Sinetrol Xpur per day).

*28€ Europe shipping by Fedex

*35€ UK delivery + custom duties

*35€ Switzerland delivery

Clinically investigated

3 proprietaries clinical trials
Double-blind, randomized, placebo-controlled & published studies

Demonstrated mechanism of action

Unique mechanism of action
Synergy of polyphenols

Healthier body composition

Body shape improvement
combined with an improved
lean-to-fat mass ratio